華南農(nóng)業(yè)大學(xué)生命科學(xué)學(xué)院導(dǎo)師：孫建偉 正文

[導(dǎo)師姓名]
孫建偉

[所屬院校]
華南農(nóng)業(yè)大學(xué)

[基本信息]
導(dǎo)師姓名：孫建偉
性別：男
人氣指數(shù)：1279
所屬院校：華南農(nóng)業(yè)大學(xué)
所屬院系：生命科學(xué)學(xué)院
職稱：教授
導(dǎo)師類型：碩導(dǎo)/博導(dǎo)
招生專業(yè)：細(xì)胞生物學(xué)、生物化學(xué)與分子生物學(xué)

[通訊方式]
辦公電話：13822222004
電子郵件：jwsun@scau.edu.cn
通訊地址：廣州天河五山路483號華南農(nóng)業(yè)大學(xué)

[個(gè)人簡述]
孫建偉，博士，教授。2010年畢業(yè)于中國科學(xué)院遺傳與發(fā)育生物學(xué)研究所，之后進(jìn)入美國佛羅里達(dá)Moffitt癌癥研究中心進(jìn)行博士后研究，2014年12月晉升為研究科學(xué)家，2015年4月被華南農(nóng)業(yè)大學(xué)引進(jìn)回國工作。孫建偉實(shí)驗(yàn)室主要以隱桿秀麗線蟲（C.elegans）和癌細(xì)胞系及小鼠為研究對象，側(cè)重于鈣池操縱的鈣流入及肌動蛋白集束蛋白Fasci調(diào)控失調(diào)在癌癥發(fā)生、轉(zhuǎn)移及擴(kuò)散中的作用機(jī)制研究。

[科研工作]
工作經(jīng)歷
2015.4--至今華南農(nóng)業(yè)大學(xué)生命科學(xué)學(xué)院教授
2014.12-2015.4Moffitt癌癥研究中心ResearchScientist
2010.12-2014.11Moffitt癌癥研究中心Postdoctor
發(fā)表論文
1.ShengchenLin,ShuangLu,MentorMulaj,BinFang,TylerSKeeley,lixinWan,JihuiHao,MartinMuschol,JianweiSun*andShengyuYang*.monoubiquitinationinhibitsthebundlingactivityofFascin.JournalofBiologicalChemistry2016,Nov22.(*correspondenceauthor)
2.Fujian.Lu,Jianwei.Sun,Heping.ChengandShengyu.Yang,Fluorescence-basedmeasurementofstore-operatedCa2+entryincancercellsusingFluo-4andconfocallivecellimaging,MethodsMolBiol,（inpress）
3.JianweiSun,ShengchenLin,TylerSKeeley,ShengyuYang.DisseminatingMelanomaCellsSurfonCalciumWaves.Molecular&CellularOncology.
20152(4).pii:e1002714
4.YuefengSun,JianweiSun,PanidaLungchukiet,WaiseQuarni,ShengyuYang,XiaohongZhang,andWenlongBai.Fe65SuppressesBreastCancerCellMigrationandInvasionthroughTip60MediatedCortactinAcetylation.ScientificReport2015Jul135:11529.doi:10.1038/srep11529.
5.JianweiSun,FujianLu,HuifangHe,JunlingShen,JaneMessina,RahelMathew,DapengWang,AmodA.Sarnaik,Wei-ChiaoChang,MinjungKim,HepingCheng,andShengyuYang.STIM1-andOrai1-mediatedCa2+oscillationorchestratesinvadopodiumformationandmelanomainvasionJournalofCellBiology.2014Nov24,207(4):535-548.(HighlightedbyJCBeditor:http://jcb.rupress.org/content/early/2014/11/10/jcb.2074iti3)
6.Jaw-YuanWang*,JianweiSun*,Ming-YiiHuang,Ming-FengHou,Yu-ShiuanWang,YanSun,Yao-TingTsai,HuifangHe,ShengchenLin,ShengyuYang,andWei-ChiaoChang.STIM1OverexpressionpromotedColorectalCancerProgression,CellMotilityandCOX-2Expression.(*theseauthorscontributedequallytothiswork)Oncogene,2015Aug1334(33):4358-67
7.XiaoZhao,SongGao,HeRen,WeiSun,HuanZhang,ShengyuYang,JianweiSun,andJihuiHao.Hypoxiainduciblefactor-1promotespancreaticductaladenocarcinomainvasionandmetastasisthroughactin-bundlingproteinfascin.CancerResearch.2014May174(9):2455-64
8.JianweiSun,HuifangHe,SmithaPillai,YinXiong,SrideviChalla,LiyanXu,SrikumarChellappanandShengyuYang.GATA3TranscriptionFactorAbrogatesSmad4TranscriptionFactor-mediatedFascinOverexpression,InvadopodiumFormation,andBreastCancerCellInvasion.JournalofBiologicalChemistry.2013Dec27288(52):36971-82
9.JianweiSun,HuifangHe,YinXiong,ShuangLu,JunlingShen,AnnaCheng,Wei-ChiaoChang,Ming-FengHou,JohnathanM.Lancaster,MinjungKimandShengyuYang.FascinProteinIsCriticalforTransformingGrowthFactorProtein-inducedInvasionandFilopodiaFormationinSpindle-shapedTumorCells.JournalofBiologicalChemistry2011,286(45):38865–38875.
10.DidiChen,HuiXiao,KaiZhang,BinWang,ZhiyangGao,YouliJian,XiayingQi,JianweiSun,LongMiaoandChonglinYang.RetromerIsRequiredforApoptoticCellClearancebyPhagocyticReceptorRecycling.Science2010,327(5970):1261-4.
11.MeiYang*,JianweiSun*,XiaojuanSun,QinfangShen,ZhiyangGaoandChonglinYang.CaenorhabditiselegansProteinArginineMethyltransferasePRMT-5NegativelyRegulatesDNADamage-inducedApoptosis.PLoSGenet20095(6):e1000514.(*theseauthorscontributedequallytothiswork)
12.YouliJian,ZhiyangGao,JianweiSun,QinfangShen,FengFeng,YudongJingandChonglinYang.RNAaptamersinterferingwithnucleophosminoligomerizationinduceapoptosisincancercells.Oncogene(2009)28,4201–4211.
13.JianweiSun,TaoLiu,BaotaiGuo,DeminJin,ManliWeng,YanbinFeng,PuXu,DelinDuanandBinWang.DevelopmentofSSRPrimersfromESTSequencesandTheirApplicationinGermplasmIdentificationofPorphraLines(Rhodophyta).EuropeanJournalofPhycology2006,41(3):329-336.
14.JianweiSun,DeminJin,ChunjiangZhou,QingkaiYang,ManliWeng,DelinDuan,PuXu,JiahaiMaandBinWang.IdentificationofPorphyraLines(Rhodophyta)byAFLP-DNAFingerprintingandMolecularMarkers.PlantMolecularBiologyReporter2005,23(3):251-262.

[教育背景]
博士博士研究生理學(xué)細(xì)胞生物學(xué)，發(fā)育生物學(xué)中國科學(xué)院遺傳發(fā)育所全日制2006-2010
碩士碩士研究生農(nóng)學(xué)作物遺傳育種青島農(nóng)業(yè)大學(xué)全日制2003-2006
學(xué)士大學(xué)本科農(nóng)學(xué)農(nóng)學(xué)萊陽農(nóng)學(xué)院全日制1999-2003

華南農(nóng)業(yè)大學(xué)

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